Evaluation of N-Butyl 2-Cyanoacrylate for the Fixation of Osteochondral Fractures

Mary Jean Gorse; D. N. Aron; G. N. Rowland; P. T. Purinton; R. E. Roberts

doi:10.1055/s-0038-1633243

Veterinary and Comparative Orthopaedics and Traumatology, Table of Contents

Vet Comp Orthop Traumatol 1991; 4(01): 11-15
DOI: 10.1055/s-0038-1633243

Original Research

Schattauer GmbH

Evaluation of N-Butyl 2-Cyanoacrylate for the Fixation of Osteochondral Fractures

Mary Jean Gorse

¹From the Department of Small Animal Medicine, University of Athens, Georgia 30602, USA

²From the Department of Anatomy and Radiology, University of Athens, Georgia 30602, USA

,

D. N. Aron

¹From the Department of Small Animal Medicine, University of Athens, Georgia 30602, USA

²From the Department of Anatomy and Radiology, University of Athens, Georgia 30602, USA

,

G. N. Rowland

³From the Department of Avian Medicine College of Veterinary Medicine, University of Athens, Georgia 30602, USA

,

P. T. Purinton

²From the Department of Anatomy and Radiology, University of Athens, Georgia 30602, USA

,

R. E. Roberts

²From the Department of Anatomy and Radiology, University of Athens, Georgia 30602, USA

› Author Affiliations

Abstract

Summary

Unstable osteochondral fractures were created on one medial femoral condyle of 39 adult rabbits. The fractures were repaired with n-butyl cyanoacrylate adhesive in 21 rabbits. The remaining fractures were not repaired. Radiographs were made at frequent intervals. The rabbits were euthanatized at 4, 6, 8, 12, and 16 weeks after surgery. The alignment and stability of the osteochondral fragments were assessed, followed by collection of sections of the medial femoral condyles for histological evaluation. Radiologically, the adhesive repaired fractures healed by primary bone union. The adhesive repaired fractures were significantly (p <0.05) better aligned and more stable than the non-repaired fractures at necropsy. Histologically, there was healing of the subchondral fracture lines of adhesive repaired fractures. The articular cartilage overlying the healing fragments was normal or had only minor surface irregularities.

Keywords

Osteochondral fracture - bone adhesive - cyanoacrylate

Full Text

References

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